ATP-binding cassette transporter A subfamily 8 is a sinusoidal efflux transporter for cholesterol and taurocholate in mouse and human liver

K Sasaki, M Tachikawa, Y Uchida, S Hirano… - Molecular …, 2018 - ACS Publications
… known substrates of ABC transporters and solute carrier (SLC) family transporters, including
… in hepatocytes and to clarify the functional roles of ABCA3 and ABCA6 in lipid homeostasis

ABC family transporters

X Liu - Drug transporters in drug disposition, effects and …, 2019 - Springer
… largest transporter families is the ATP-binding cassette (ABC… are expressed in various
tissues such as the liver, intestine, … Mouse studies confirmed that the Abcc1 −/− mice exhibited …

Identification of miR-9-5p as direct regulator of ABCA1 and HDL-driven reverse cholesterol transport in circulating CD14+ cells of patients with metabolic syndrome

S D'Amore, J Härdfeldt, M Cariello… - Cardiovascular …, 2018 - academic.oup.com
… of the ATP-binding cassette transporter A1 (ABCA1), a key player in cholesterol efflux (CE). …
glucose and lipid homeostasis. MS is associated with atherosclerosis, fatty liver, type 2 …

[HTML][HTML] Hepatic microRNAome reveals potential microRNA-mRNA pairs association with lipid metabolism in pigs

J Liu, C Ning, B Li, R Li, W Wu, H Liu - Asian-Australasian journal …, 2019 - ncbi.nlm.nih.gov
ATP-binding casette A4, and stearyl-CoA desaturase. Thus, these miRNAs were the promising
candidates for lipid … To further identify candidate miRNAs involved in porcine hepatic lipid

MicroRNA profiling identifies miR-196a as differentially expressed in childhood adrenoleukodystrophy and adult adrenomyeloneuropathy

N Shah, I Singh - Molecular neurobiology, 2017 - Springer
… as ATP-binding cassette peroxisomal membrane transporters [13… These studies document
that cell-specific induction of … Overexpression of miR-196a was reported to protect against liver

… of liver x receptor target genes Apolipoprotein E and ATP-binding cassette transporter A1 on beta-amyloid dependent pathology in Alzheimer's disease model mice

A Carter - 2017 - d-scholarship.pitt.edu
ATP-binding cassette transporter A1 (ABCA1) and APOE are major LXR target genes involved
in lipid and cholesterol generation and transport … We determined that Abca1ko mice have …

[HTML][HTML] Liver X receptors and male (In) fertility

S Jarvis, C Williamson, CL Bevan - International Journal of Molecular …, 2019 - mdpi.com
… as master regulators of lipid homeostasis by functioning as ‘… tissue specific and potentially
cell specific variation in oxysterol … LXR-upregulated ATP binding cassette (ABC) transporters: …

[图书][B] Engineering of Two-Color ATP-Binding Cassette Biosensor Proteins for Discovery of Novel Substrates and Modulators

B Osa-Andrews - 2018 - search.proquest.com
… Studies conducted on mouse P-gp and bovine MRP1 reveal … Three ABC transporters highly
expressed in the liver, the gut … /inhibitor/activator candidates and identified eight compounds …

Circular RNAs in metabolism and metabolic disorders

Y Zeng, Z Zheng, F Liu, G Yi - Obesity Reviews, 2021 - Wiley Online Library
… Indeed, transgenic mice with pancreatic islet β-cell-specific … These factors and ATP binding
cassette (ABC) transporters … is in sustaining glucose and lipid homeostasis, and this review …

[HTML][HTML] Remembering your A, B, C's: Alzheimer's disease and ABCA1

CT Lewandowski, MS Laham, GRJ Thatcher - Acta Pharmaceutica Sinica B, 2022 - Elsevier
… The function of ATP binding cassette protein A1 (ABCA1) is … , have shown positive effects
in AD mouse models; however, … , such as lipid metabolism and immune signaling in the liver, …